SINERGY
Supported by National Research Foundation

ABOUT US

Introduction

Synthetic biology is a maturing scientific discipline that combines science and engineering in order to design and build new biological parts, devices and systems. Synthetic biology offers enormous opportunities to benefit society with promising applications in areas such as energy, healthcare and the environment. Launched in September 2016, the Singapore Consortium for Synthetic Biology, SINERGY aims to consolidate Singapore’s capabilities in synthetic biology and harness synergies across industry sectors to create a vibrant and globally connected bio-based economy in Singapore. Efforts to foster interactions and co-development between the industry, universities and research institutes will encourage user-inspired research, augment manpower development, as well as speed up the translation of expertise in synthetic biology for industry applications. SINERGY is supported by the National Research Foundation and hosted at the National University of Singapore.

Objectives

  • Upgrade industry technological abilities through active engagement and co-development among industry, universities and research institutes
  • Harness synergies across R&D collaborative projects
  • Facilitate manpower deployment from institutes of higher learning to industries
  • Provide a one-stop, go-to national resource centre for companies and members

Key areas of interest

  • Advanced Manufacturing for Specialty Chemicals
  • Protein and Enzyme Engineering
  • Biosensors and Cell-Free Systems
  • Biomimetics
  • Synthetic Genomics
  • Proprietary Strain Construction and Optimization

BioFoundry

NUS Synthetic Biology Foundry

NUS Synthetic Biology Foundry represents a hallmark of synthetic biology research in driving foundational science towards translational clinical and industrial biotechnology applications. Equipped with state-of-the-art robotic system that is interfaced with various high throughput analytical instruments, the Foundry enables systematic (re)designing, building, testing and learning of synthetic biological systems on a highly efficient, automated manufacturing platform. By fostering advanced research through international collaborations, the Foundry aims to become a central hub for cutting-edge synthetic biology research in Asia.

Facilities

Gas Chromatography
Mass Spectrometer
(GC-MS)

Ultra-High Performance Liquid
Chromatography System
(UHPLC)

Quadrupole Time-of-Flight
Liquid Chromatography/
Mass Spectrometry System
(Q-TOF)

Fluorescence Activated
Cell Sorter
(FACS)

Flow
Cytometry
Analyser

Real-Time Polymerase
Chain Reaction
(PCR) System

Microplate
Reader

Lab-scale
Biorectors

For information on facility usage,

please contact us.

MEMBERS

Industry Members

 
 
 
 
 
 
 
 
 
 

Academic Members

 
 
 
 
 
 
 
 

EVENTS

Jan
Feb
Mar
Apr
May
June
July
Aug
Sept
Oct
Nov
Dec

Medical applications of innovative mussel protein bioadhesives

Marine mussel adhesion is known to be mediated by adhesive proteins, which are secreted through the mussel byssus and have great potential as biologically and environmentally friendly adhesive biomaterials due...
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Cha Hyung Joon

Design, Construction, and Analysis of a Synthetic Minimal Bacterial Cell

The minimal cell is the hydrogen atom of cellular biology. Such a cell, because of its simplicity and absence of redundancy would be a platform for investigating just what biological components are required for life, and how those parts work together to make a living cell.
Dr John I. Glass

GT (Sialyltransferase and fucosyltransferase) mutagenesis and Metabolic Engineering for the synthesis of 3‘/6‘-SL and 2‘/3-FL from human Milk

Oligosachharides in human milk(HMOs) have various useful biological functions for infant and applications in industry. Among them, sialyllactose(3’/6‘-SL) and fucosyllactose(2‘/3-FL) draw our atttention. To produce these oligosaccharides in large quantity,...
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Kim Byung Gee

Biocatalysis of soybean isoflavonoids using various oxidoreductases: synthesis of hydroxyl-equol derivatives

Soybean plant originated from Manchuria are known to be spread out in world, and the regions from North Korea to Manchuria have the highest diversity of the soybean species worldwide.
Kim Byung Gee

Biotechnology to Help Achieve the UN’s Sustainable Development Goals

We are living in a world that is so rapidly changing with a lot of global risks. To make better state of the world, the United Nations announced 17 sustainable...
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Sang Yup Lee

Bio-inspired Electronic Skins

Electronic sensor skins are active area of research for many groups globally due to its potential to enable dramatic changes in how we interact with the digital environment. For example,...
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Benjamin C.K. Tee

“Me? An Entrepreneur?”

To make the world a better place, we need great solutions.  Entrepreneurs around the world have been instrumental in advancing technological processes, disrupting traditional industries and creating impactful change.  Do...
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Brian SH Koh

Genome-wide target specificity of CRISPR RNA-guided base editors

Adenine Base Editors (ABEs), composed of the Cas9 nickase derived from S. pyogenes and engineered adenine deaminases derived from E. coli, enable efficient adenine-to-guanine single-nucleotide conversions in human cells.
Jin-Soo Kim

Metabolic engineering and regulation of the bosynthesis of artemisinin, the most potent anti-malaria compound, in Artemisia annua L.

Artemisinin, an endoperoxide-containing sesquiterpene lactone isolated from Artemisia annua L., is extensively used in treating malaria. The artemisinin-based combination therapy (ACT) is recommended by World Health Organization (WHO) to combat...
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Kexuan TANG

Aberrant Stem/Progenitor Cell Behavior During Aging And Cancer

Adult stem cells, with the unique property of performing self-renewal and multi-lineage differentiation, are essential for maintaining homeostasis and function of various organs in our body, including the hematopoietic system...
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Derrick Ong

Building Complex Protein Functions at the Intersection of Nanofabrication and Synthetic Biology

Proteins are the most versatile among the various biological building blocks. However, the strength of proteins – their versatility and specific interactions – also complicates and hinders their systematic design...
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Wilfred Chen

Biofilm Biology-Informed Biofilm Engineering

Biofilm represents the predominant mode of growth of microorganisms in natural, engineered and medical habitats. Microbial biofilms can be either beneficial or detrimental in different settings. While an enhanced understanding...
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Cao Bin

Innovations in Cell-Free Synthetic Biology

Cell-free transcription-translation systems were originally applied towards in vitro protein production. More recently, synthetic biology is enabling these systems to be used within a systematic design context for prototyping DNA...
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Richard Kelwick

Single Cell Clinical Analysis for Precision Medicine by Using Integrative Microfluidics

Precision medicine refers to giving the right therapeutics, to the right patient, at the right time. In the context of cancer, successful implementation of precision medicine, requires treatment individualization not...
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Chia-Hung Chen

Synthetic small intestines for treating and studying intestinal disease

In recent years, it has become widely accepted that in vitro intestinal models enable improved studies of intestinal function in an ethical and well-controlled manner.
John C. March

From Gene to Activity – Exploiting the Potential of Nestlé Culture Collection

Nestlé boasts a culture collection of more than 3000 food-grade strains (Nestlé Culture Collection, NCC) that has been integrated into an R&D network covering microbiology, fermentation,...
Jeroen Muller

Getting your device onto the Singapore market

This talk provides an introduction to the product registration process by HSA, covering the documentation requirements for the various device risk classifications.
Daniel Yap

Synthetic Biology – a Key Driver of the BioEconomy through BioDesign and Industrial Translation

Synthetic biology/engineering biology is highly disruptive technology that can be applied across a wide range of fields - well beyond the scope of traditional industrial biotechnology. It is seen as a key driver of the BioEconomy and is part...
Richard I Kitney

Rapid acquisition and model-based analysis of cell-free transcription-translation reactions from non-model bacteria

Cell-free transcription/translation systems (known as CFPS or TX-TL) have recently been re-evaluated as a promising platform for enabling synthetic biology research and applications. In particular CFPS has been shown to provide a...
Paul Freemont

Salivary gland cancers: A rare cancer as a platform for precision medicine

Salivary gland cancer is a rare cancer with various subtypes. Expanding knowledge in genomics shed a new light on the rare cancers - current understanding, future directions ...
Hyunseok Kang

Protein Engineering, the unsung hero of next generation sequencing

Illumina sequencing technology has reduced the cost of genome sequencing from ~$1B two decades ago to ~$1K today..
Dr Sergio Peisajovich

Contact Us

Membership

The Consortium membership is open to companies that:

  • Are actively involved in synthetic biology-related manufacturing, design or R&D
  • Apply synthetic biology approaches in their product or manufacturing processes
  • Provide technologies, products or services that support synthetic biology applications
                                                                            Non Start-Up Company Start-up Company
Membership Entrance Fee S$10,000 S$1,000
Annual Membership Fees S$1,000 S$1,000

Note:

a) Companies that join in the inaugural year of SINERGY, i.e. 2017, are regarded as founding members.

b) The Membership Fee is inclusive of Goods and Services Tax.

c) The Membership Fee shall be payable in advance of the applicable membership year within thirty (30) days from the date of invoice issued by NUS.

d) The effective date of membership is 1 January of the year of application, as determined in accordance with Sections 3 and 4 of the Membership Application Form, and membership is effective till 31 December of the same calendar year.

e) Membership is renewable on an annual basis, in advance, and shall be effective from 1 January of the following year, regardless of the date of first joining.

For information on membership fees,

please contact us.