Genome-wide target specificity of CRISPR RNA-guided base editors

17 Feb 2019
14 Mar 2019 | 2pm
CeLS Auditorium

Genome-wide target specificity of CRISPR RNA-guided base editors

Adenine Base Editors (ABEs), composed of the Cas9 nickase derived from S. pyogenes and engineered adenine deaminases derived from E. coli, enable efficient adenine-to-guanine single-nucleotide conversions in human cells.