Across space and time – Spatial and longitudinal analysis of the mouse gut microbiota
The laboratory mouse remains the most widely used model for microbiome research and yet some facets of the mouse microbiome remain poorly investigated. This concerns particularly the cultivation of anaerobic mouse gut microorganisms as well as the spatial and temporal compositional changes of the mouse gut microbiota. In this seminar insights will be presented into the murine microbial gut biogeography and the longitudinal microbiota changes across the lifespan of adult laboratory mice. The potential implications of the findings for the analysis of the human microbiome and the development of microbiome therapeutics will be discussed.