The Importance of Standards, Foundries and Information Systems in BioDesign and Industrial Translation
The seminar will address the role of standards, foundries and information systems in relation to BioDesign and industrial translation. These will be discussed against the background of the development of BioEconomy strategy and associated roadmaps – together with the need for a low carbon economy. Synthetic biology/engineering biology will be introduced as platform technology and BioDesign in the context of prototyping and the DBTL cycle. One important endpoint of BioDesign is industrial translation. This will be discussed in relation to of reproducibility and reliability – and how a strategy for engineering biology from the laboratory to the market is being developed. Technical standards and Biofoundries are important elements of this strategy. The next section of the seminar will consider the role of characterisation and Information systems. A standard for capturing characterisation data, in the context of information systems and data integration, will be described in relation to Biofoundries. This will be discussed in terms of characterisation protocols relating to constitutive promoters and the development of associated datasheets. A case study of the design of a lycopene pathway will be presented in the context of toolkits, Information Systems and the design of experiments (DoE). The final section of the seminar will consider how the overall strategy relates to the development of industrial manufacturing in the context of engineering biology.