Innovations in Cell-Free Synthetic Biology
Cell-free transcription-translation systems were originally applied towards in vitro protein production. More recently, synthetic biology is enabling these systems to be used within a systematic... Read More
Biofilm Biology-Informed Biofilm Engineering
Biofilm represents the predominant mode of growth of microorganisms in natural, engineered and medical habitats. Microbial biofilms can be either beneficial or detrimental in different... Read More
Building Complex Protein Functions at the Intersection of Nanofabrication and Synthetic Biology
Proteins are the most versatile among the various biological building blocks. However, the strength of proteins – their versatility and specific interactions – also complicates... Read More
Aberrant Stem/Progenitor Cell Behavior During Aging And Cancer
Adult stem cells, with the unique property of performing self-renewal and multi-lineage differentiation, are essential for maintaining homeostasis and function of various organs in our... Read More
Metabolic engineering and regulation of the bosynthesis of artemisinin, the most potent anti-malaria compound, in Artemisia annua L.
Artemisinin, an endoperoxide-containing sesquiterpene lactone isolated from Artemisia annua L., is extensively used in treating malaria. The artemisinin-based combination therapy (ACT) is recommended by World... Read More
Genome-wide target specificity of CRISPR RNA-guided base editors
Adenine Base Editors (ABEs), composed of the Cas9 nickase derived from S. pyogenes and engineered adenine deaminases derived from E. coli, enable efficient adenine-to-guanine single-nucleotide... Read More
“Me? An Entrepreneur?”
To make the world a better place, we need great solutions. Entrepreneurs around the world have been instrumental in advancing technological processes, disrupting traditional industries... Read More
