Protein Engineering, the unsung hero of next generation sequencing

Structural evidence for a functional actin cytoskeleton in Asgard archaea

The origin of the eukaryotic cell is unresolved. Metagenomics sequencing recently provided evidence for several potential eukaryotic gene homologs in the Asgard archaea. However, many of these eukaryotic-like sequences are highly divergent and the organisms have yet to be imaged or cultivated, bringing in to question whether these archaea exhibit eukaryotic characteristics.