Human physiology and pathophysiology, such as such as in metabolic diseases and microbiome-host interactions, often involve systemic interactions between multiple tissues. Multi-organ perfusion systems offer the unique opportunity to mimic different physiological systemic interactions...
Nanopore microscopy is a high-throughput, single-molecule technique capable of detecting the shape, structure and chemical properties of individual biomolecules and complexes, including DNA, proteins and... Read More
Cell-free transcription/translation systems (known as CFPS or TX-TL) have recently been re-evaluated as a promising platform for enabling synthetic biology research and applications. In particular... Read More
The origin of the eukaryotic cell is unresolved. Metagenomics sequencing recently provided evidence for several potential eukaryotic gene homologs in the Asgard archaea. However, many of these eukaryotic-like sequences are highly divergent and the organisms have yet to be imaged or cultivated, bringing in to question whether these archaea exhibit eukaryotic characteristics.
Mass spectrometry (MS) is an important analytical technique with high sensitivity and selectivity. However, all known ambient MS ionization methods are significantly hindered by ion suppression that is caused by ion charge competition other than the target molecules.
The number of proteins in the UniProt database (>182M sequences in Release 2019_10) is increasing with a doubling time of ~2.5 years; however, ≥50% of the proteins have uncertain, unknown, or incorrect functions. This lecture will describe...
The dipteran Tephritidae family includes dozens of major agricultural pest species, including the mediterranean fruitfly Ceratitis capitata (medfly). The genetic control of these species can be based on the release of sterile males, following their sexing from females.
According to the Biotechnology Innovation Organisation, BioTech is “technology based on biology – harness[sing] cellular and biomolecular processes to develop technologies and products that help... Read More