Xiaodan Li is a membrane protein biochemist and structural biologist. She studied biology and biotechnology at the University of Beijing and Zürich, and got her PhD at the ETH Zürich Institute of Microbiology, Switzerland. She did her postdoctoral research at the Rockfeller University and Columbia University in New York. She has established the membrane protein structure biology group at Paul Scherrer Institute since 2002. Her research lab focuses on: 1. Functional expression of mammalian membrane protein in milligram amount using protein engineering; 2. Structure studies of voltage/ligand-gated channels and G-Protein Coupled Receptors (GPCRs) with 3D and 2D crystals using X-ray crystallography, cryo-EM and XFEL; 3. Identification and characterization of human disease-related membrane protein complexes, involved in energy conservation and signalling transduction by mass spectrometry, SAXS and cryo-EM and Total Internal Reflection Fluorescence microscopy (TIRF); 4. Development of nanomaterial tools for detecting membrane protein conformational changes in the lipid bilayer aiming for time-resolved studies using XFEL.